Solarbio Mouse Insulin Elisa Kit

Mouse Insulin Elisa Kit

NO : SEKM-0141

Specie :

Topo
Tipo di test :

Sandwich di fase solida Elisa
Sensibilità :

0.09 ng/mL
Intervallo di rilevamento :

0.17-5.5 ng/mL
Lunghezza del dosaggio :

3.5H
Tipo di campione :

Siero; Plasma; Supernatante di coltura cellulare; Urine; Tessuto.
Nome lungo :

Insulin
Sinonimi :

IDDM; IDDM1; IDDM2; ILPR; INS; Insulin; IRDN; MODY10;
Sfondo :

Insulin and the IGFs are members of the insulin family of molecules. IGF-I and II are structurally homologous to proinsulin, and can be thought of as taking the shape of an exaggerated, inverted letter G. Interchain disulfide bonds link sections of the G. The single chain insulin propeptide consists of a 30 amino acid B chain (aa 2554), a C-peptide (aa 5589), e a 21 aa A chain (aa 90110). Removal of the C-peptide by proteolysis enables the formation of mature Insulin, a disulfide linked heterodimer of the A and B chains. Circulating C-peptide levels are elevated in hyperinsulinism, obesity, and type II diabetes.