Especificación
Especies :
Humano
Tipo de ensayo :
ELISA tipo sándwich en fase sólida
Sensibilidad :
46 PG/ml
Rango de detección :
93.8-6,000 PG/ml
Longitud del ensayo :
3.5h
Tipo de ejemplo :
Suero; Plasma; Sobrenadante de cultivo celular.
Soluble E-selectin
synonyms :
SELE; CD62E; ELAM; ELAM1; ESEL; LECAM2; Selectin E
Fondo :
The Selectin family is comprised of three members, E-Selectin, L-Selectin, and P-Selectin. E-Selectin [endothelial leukocyte adhesion molecule-1 (ELAM-1), CD62E] is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha.
The human and rat proteins share approximately 67% amino acid sequence identity.
The mouse and rat proteins share approximately 78% amino acid sequence identity. L-Selectin (Leukocyte Selectin, LAM-1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L) is expressed constitutively on a wide variety of leukocytes.
Two forms of L-Selectin have been reported, apparently arising as a result of post-translational modifications. Human and mouse L-Selectin share 76% amino acid sequence identity. Human P-Selectin (GMP-140, LECAM-3, PADGEM, CD62P) is expressed by activated platelets and endothelial cells.
The extracellular domains of human and mouse P-Selectin share approximately 73% amino acid sequence identity.
Reseñas
Aún no hay reseñas.